Straightforward answers to your questions
about living with age-related macular degeneration

How to Manage Age-Related Macular Degeneration

A new report from the renowned Wilmer Eye Institute at Johns Hopkins-
one of the nation’s leading ophthalmology centers

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Your eyesight is a precious gift that should last a lifetime. Unfortunately, for the seven million people in the United States affected with age-related macular degeneration (AMD), the loss of vision is a very real threat.

AMD is the leading cause of severe and irreversible loss of central vision in people over age 50. For these people, AMD can seriously impact quality of life, making it difficult to read … drive a car … or even see someone’s face.

But there is GOOD NEWS: Although AMD is a chronic disease and can advance as a person ages, early detection and close monitoring by an experienced ophthalmologist can limit or halt its progression.

And in the past decade there has been a revolutionary advance in the treatment of the most severe form of AMD - the type called neovascular, or wet, AMD. Today we have new ophthalmic medications that are giving hope to patients with wet AMD.

If you're reading this letter right now, chances are you or a loved one has been diagnosed with AMD. If so, it's critically important to learn everything you can about your condition so you can make informed decisions, partner with your ophthalmologist effectively, ask the right questions about your treatment, and understand the answers.

To help you in this quest, we have asked Johns Hopkins specialist Diana V. Do, M.D., to share her wisdom and hands-on experience treating AMD patients in a new in-depth report, How to Manage Age-Related Macular Degeneration.

Associate Professor of Ophthalmology at the Wilmer Eye Institute at Johns Hopkins, Dr. Do is ideally positioned to help you understand and manage your AMD. Dr. Do maintains an active clinical and surgical practice at Johns Hopkins and specializes in the treatment of wet AMD, as well as treatments for retinal detachment and diabetic eye disease.

The information in How to Manage Age-Related Macular Degeneration is so critical to your wellbeing that we are making it available to you instantly in a digital PDF download. Simply click the order button below, and in a few moments you can begin reading this important report!

Tackling the BIG Issues in AMD

What will you learn in How to Manage Age-Related Macular Degeneration? In the opening pages, Dr. Do takes a close look at AMD. In clear, straightforward language she explains how the eye works, the role of the retina and key characteristics of the two types of AMD: dry, the most common type, and wet, the more serious form and the primary cause of AMD-related vision loss.

Dr. Do addresses questions that may be on your mind as you confront this serious condition:

• Is it possible to have both dry and wet AMD at the same time?
• What is the likelihood that someone with dry AMD will develop impaired vision?
• What degree of vision loss can occur in someone with wet AMD?
• What risk factors are associated with developing AMD?
• Can AMD be prevented?
• Is there any evidence to show that antioxidants can slow the progression of AMD?
• What about omega-3 fatty acids and B vitamins?
• If early-stage dry AMD has no symptoms, how is it diagnosed?
• Are both eyes usually affected at the same time?
• How does an ophthalmologist diagnose AMD?
• What are the clinical signs of wet AMD?
• I’ve heard of a new imaging test called optical coherence tomography (OCT). What is it and how is it used?
• How is OCT used in conjunction with fluorescein angiography?
• What key questions should I ask my ophthalmologist about my AMD diagnosis?

Halting the Progression of AMD -
What Works? What’s in the Pipeline?

The treatment and prognosis for AMD hinge on the type of AMD and how advanced it is at the time of diagnosis. In How to Manage Age-Related Macular Degeneration, Dr. Do provides a detailed look at current treatments for dry and wet AMD. This information can help you better understand and discuss YOUR treatment regimen with your doctor …

• If you have dry AMD and have geographic atrophy, can anything be done to prevent vision loss?
• What have we learned about the effect of dietary supplements on the risk and progression of AMD from the Age-Related Eye Disease Study (AREDS)?
• Are there any promising experimental therapies for treating advanced dry AMD?
• How do the drugs called VEGF inhibitors-which include Lucentis and Avastin-improve the prognosis for people with wet AMD? How do these new drugs work?
• Are Lucentis and Avastin equally effective in treating AMD?
• Is it safe to take Avastin for wet AMD even though it’s not yet FDA approved for this condition?
• What are the advantages of the drug called VEGF Trap-Eye, also known as Eylea, which was recently approved by the FDA?
• What should I expect from an injection of an anti-VEGF drug?
• What is the optimal dosing schedule with an anti-VEGF drug-and how long does a treatment regimen last?
• A phase-2 clinical trial of a drug that targets platelet-derived grown factor, or PDGF, is underway. What is PDGF and how might this new drug help patients with AMD?

When should you seek the help of a low-vision specialist? Even if you’re responding well to anti-VEGF therapy, a low-vision specialist can help you maximize your vision and improve your quality of life.

And there are also numerous devices designed to help people with low vision see better and increase independence, including desktop video magnifiers … handheld magnfiers … scanning and playback … computers … and an implantable miniature telescope (IMT) for AMD … all of which are reviewed in the final chapter of How to Manage Age-Related Macular Degeneration.

Direct to You From Johns Hopkins – America’s #1 Hospital

How to Manage Age-Related Macular Degeneration is written to give you unprecedented access to the expertise of the hospital ranked #1 of America's Best Hospitals by U.S. News & World Report. And the acclaimed Wilmer Eye Institute at Johns Hopkins has long been recognized for bringing together ophthalmologists consistently ranked by their peers as among the finest internationally, with a specially trained and highly experienced team of nurses, technicians and staff cited by patients for their knowledge, responsiveness and sensitivity. You simply won't find a more knowledgeable and trustworthy source of the medical information you require.

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