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The War Against Cholesterol: Are Statin Drugs The Saving Grace?

Americans are failing to manage their cholesterol through diet and daily exercise. More than 13 million of us have coronary heart disease-arteries clogged with deposits of cholesterol, fats, calcium and other substances found in the blood. In a country with epidemic heart disease, the number-one killer for both genders, the emergence of a new class of drugs that helps optimize blood cholesterol levels has been heralded as a potential "magic bullet." But are these newcholesterol-lowering medications, known as statin drugs, living up to their promise?

Statin medications are indeed one of the most important medical advances of the 21st century. They work by blocking a key enzyme the liver needs to manufacture cholesterol, dramatically improving cholesterol levels. They also help stabilize the lethal mixture of cholesterol and other fatty deposits, known as plaques, that may have already accumulated in your blood vessels. Statins help prevent plaques from breaking off and causing a dangerous obstruction or blood clot that can lead to heart attack or stroke.

Only your doctor can prescribe a statin and help you determine which one is best for you. Here are several things you should know before taking statins:

  • If you have high cholesterol levels without any other known cardiovascular risk factors, it is important to try a few lifestyle changes, such as exercising more and improving your diet, before embarking  on a statin regimen.
  • Elevated cholesterol levels may not be the sole reason your  doctor suggests statins. You may also need them if you have angina (chest  pain) or have suffered a heart attack, if you have already had  angioplasty or bypass surgery, or if you have diabetes.
  • Statin drugs have a solid safety record, but they do come with some potential side effects, including a serious muscle tissue disorder.  Your doctor should monitor your progress carefully.
  • If you already take a statin but have not yet achieved your  cholesterol goals, talk to your doctor about increasing the dosage or  switching to a different statin. You might respond differently to a  different statin, and it may take some experimentation to find the one that's  right for you.
  • For a copy of the FREE Johns Hopkins Special Report Seven Keys to Reduce Cholesterol, please visit http://www.hopkinsreports.com/cholesterol.




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    About the John Hopkins White Papers

    The John Hopkins White Papers (on subjects including arthritis, back pain and osteoporosis, coronary heart disease,  depression and anxiety, diabetes, heart attack prevention, hypertension and  stroke, lung disorders, memory, nutrition and weight control, prostate  disorders and vision) are published annually in association with the Johns Hopkins  Medical Letter: "Health After 50," published monthly since 1998.

    The goal of the White Paper Program, first launched in 1992, is to help keep consumers up to date with the latest breakthroughs in each of the medical conditions in the series. Our Johns Hopkins specialists review the latest research, and offer readers cutting-edge health news, information and advice in clear, plain English, free from bias and sensationalism.
     

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