The Johns Hopkins
Memory Bulletin

Dr. Rabins has spent his career studying mental disorders in the elderly. Dr. Rabins is co-director of the Division of Geriatric Psychiatry and Neuropsychiatry at the Johns Hopkins School of Medicine, as well as a professor of psychiatry with a joint appointment in the Department of Internal Medicine and School of Hygiene and Public Health. His current research includes the development of scales to measure impairment in people with severe dementia and the study of visual hallucinations in a variety of psychiatric and neurological conditions. Along with Nancy L. Mace, he is the coauthor of The 36-Hour Day: A Family Guide to Caring for Persons With Alzheimer's Disease, Related Dementing Illnesses, and Memory Loss in Later Life. (Warner Books, 2001).

MEDICAL ADVISORY BOARD

We have assembled a prestigious medical advisory board comprised of faculty members and other researchers at Johns Hopkins to provide you with information that can improve your life.

Marilyn S. Albert, Ph.D., a Professor of Neurology and Psychiatry at Johns Hopkins, is a distinguished researcher in cognitive changes and early identification of Alzheimer's disease.

Jason Brandt, Ph.D., is Professor of Psychiatry and Behavioral Sciences at Johns Hopkins and Director of the Division of Medical Psychology and Director of the Cortical Function Laboratory at the Johns Hopkins Hospital. Dr. Brandt is a Fellow of the American Psychological Association and Diplomate of the American Board of Clinical Neuropsychology.

Constantine Lyketsos, M.D., a geriatric psychiatrist, is a Professor of Psychiatry and co-director, Division of Geriatric and Neuropsychiatry Director of the Johns Hopkins Neuropsychiatry and Memory Group and the Comprehensive Alzheimer Program.

Guy McKhann, M.D., is Director of the Zanvyl Krieger Mind/Brain Institute at The Johns Hopkins University and Founding Director of the Department of Neurology at The Johns Hopkins University School of Medicine.

Donald L. Price, M.D., is a professor of Pathology, Neurology, and Neuroscience at the Johns Hopkins University School of Medicine. Dr. Price's research group at Hopkins was the first to identify the degeneration of neurons in the basal forebrain cholinergic system in cases of Alzheimer's. This eventually led to neurobiological investigations of this brain circuit and ultimately to the development of the cholinesterase inhibiting drugs that are being used to battle the symptoms of Alzheimer's.

If you or someone you love is facing any one of these health challenges, get the expert medical guidance you need in The Johns Hopkins Memory Bulletin:

Age-Associated Memory Impairment

Alzheimer’s Disease

Amnesia

Coping With Caregiving

Creutzfeldt-Jakob Disease

Dementia

Dementia With Lewy Bodies

Frontotemporal Dementia

Huntington’s Disease

Memory Loss as a Medication Side Effect

Memory Loss Associated with Depression

Memory Loss Associated with Medical Conditions

Mild Cognitive Impairment

Vascular Dementia

The Johns Hopkins Memory Bulletin
Inflammation and Alzheimer's Disease
Personal Essay: Placing My Father in an Alzheimer's Care Facility

For over eight years, Dr. Peter V. Rabins and his fellow specialists at the Division of Geriatric Psychiatry and Neuropsychiatry at the Johns Hopkins School of Medicine have been bringing you the latest news and most cutting-edge treatments for Alzheimer's Disease and other forms of dementia and memory loss in The Johns Hopkins Memory Bulletin.

In the Inflammation and Alzheimer's Disease issue, you'll receive a thorough overview of how chronic, low-grade inflammation is increasingly being associated with a wide variety of severe long-term health conditions, including heart disease, diabetes, and Alzheimer's disease.

You'll also receive the Personal Essay, "Placing My Father in an Alzheimer's Care Facility" by prominent journalist Kathleen Clary Miller. This moving personal essay does caregivers a great service by discussing many of the difficult physical and emotional challenges you face daily, and encouraging you to share your experiences.

In the in-depth Special Report Inflammation and Alzheimer's Disease, author Juan Tronscoso, MD, Associate Professor of Pathology and Neurology at The Johns Hopkins University School of Medicine, and Co-Director of the Alzheimer's Disease Research Center, gives you the latest progress on his research.

Dr. Tronscoso's studies are aimed at understanding how normal aging affects the brain, and how Alzheimer's Disease and other degenerative disorders can damage the brain and cause cognitive impairment.

Learn the answers to your crucial questions about the link between inflammation and Alzheimer's disease, including:

• What is inflammation?
• Does the kind of systemic inflammation that causes atherosclerosis (clogged arteries) also contribute to the development of Alzheimer's Disease (AD)?
• What is currently thought to be the role of amyloid-beta in AD?
• The inflammation theory of AD.
• An overview of the research supporting the inflammation theory of AD.
• Alzheimer's disease risk factors, and what steps you can take NOW to reduce your risk.
• Can the type-2 diabetes drug Avandia help reduce the risk of AD?
• What's the best evidence that Alzheimer's disease is an inflammatory condition?
• Do people who take a daily baby aspirin to prevent heart attacks and strokes have a lower risk of Alzheimer's disease?
• What is the most effective NSAID (Non-Steroidal Anti-Inflammatory Drug) for relieving the inflammation which may contribute to AD?
• What do you make of a recent prospective Johns Hopkins study reporting that naproxen (Aleve) is no better than placebo at preventing the onset of Alzheimer's disease?
• What do you make of other studies that discount the benefits of NSAIDs for preventing Alzheimer's disease?
• What other evidence suggests that inflammation plays a key role in the development of Alzheimer's disease?
• Since there's a close connection between high cholesterol levels and Alzheimer's disease, do drugs used to lower cholesterol (statin drugs like Lipitor, Crestor and Zocor) have a beneficial effect in lowering AD risk as well?
• Do statin drugs have anti-inflammatory effects?
• What other medications may decrease the risk of developing Alzheimer's disease?

In your information-packed issue Inflammation and Alzheimer's Disease, you will also discover:

• What general lifestyle advice do you have to help lower the inflammatory burden and the potential risk of Alzheimer's disease?
• Do you have any other general lifestyle recommendations for preventing Alzheimer's Disease?
• What are some of the nutrients and supplements that may lower inflammation and the potential risk of Alzheimer's disease?
• Are any specific diets more likely to reduce inflammation and the potential risk of Alzheimer's disease?
• What do you make of research showing that inflammation may actually be protective?
• Is it possible that the body's natural inflammatory processes have a role in combating Alzheimer's disease?
• What are the future prospects for anti-inflammatory approaches in Alzheimer's disease?

..and much more.

This is essential reading if you're concerned with how your health, diet, and overall lifestyle can contribute to Alzheimer's disease, and what steps you can take NOW to prevent Alzheimer's.

Order now, download in minutes, to start using what you learn immediately to take control of your health to protect against age-related memory loss and Alzheimer's Disease.

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Those who already subscribe to The Johns Hopkins Memory Bulletin will have already received Inflammation and Alzheimer's Disease (Fall 2007), but other subscribers and visitors to this website missed out on this crucial health information once all the printed issues were sold out.

Thanks to this special offer, you can now get the instant PDF digital download edition of Inflammation and Alzheimer's Disease for 50% off the list price.

That's right, you'll get 48 pages of invaluable memory and memory loss information direct from Hopkins' expert panel of specialists at Johns Hopkins, ranked America's #1 Best Hospital for 19 consecutive years.

Just look at all you'll get in the Inflammation and Alzheimer's Disease issue:

TABLE OF CONTENTS

Doctor Rabins' Letter:

• Stress And Cognitive Impairment
• The Mediterranean Diet And AD
• Memory Problems From GERD? (Gastroesophageal Reflux Disease)

Personal Insights:

• One Lie At A Time: Putting My Father in an Alzheimer's Care Facility

In-Depth Report:

• Inflammation And Alzheimer's Disease

Grand Rounds:

• What To Do If Stealing Is Suspected At Your Loved One's Nursing Home
• Should An AD Patient Be Sedated For Nasty Behavior?
• Withholding Medical Care In The Final Stages Of AD?
• How To Cope With Caring Issues When Far Away
• The Importance Of Taking Alzheimer's Medications Consistently
• Selecting An Appropriate Nursing Home
• Caregiving Difficulty: What Can I Do If My Loved One No Longer Qualifies For Hospice Care
• What Things Do We Need To Consider When Starting My Relative On Another AD Drug?

In addition to the Special Report Inflammation and Alzheimer's Disease, in this issue of The Johns Hopkins Memory Bulletin, you'll also receive "One Lie At a Time: Placing My Father In An Alzheimer's Facility."

This moving personal essay by the prominent journalist Kathleen Clary Miller deals in detail with her own personal physical and emotional challenges in coping with her 89-year old father and his development of Alzheimer's Disease.

As the Medical Editor Dr. Rabins states in his introduction to this essay, "Alzheimer's Disease eventually touches on so many aspects of our lives that it provides a mirror in which we can see our relationships with those we love, the strengths and limitations of our current health care system, the financial challenges of caring for someone with a chronic illness, and how important many things really are that we take for granted in everyday life."

This personal essay will hopefully offer you support and the sense that you are NOT alone in your struggle to deal with the complex issues of being a caregiver for an Alzheimer's patient.

The Inflammation and Alzheimer's Disease issue is essential reading for anyone who needs the latest news on Alzheimer's disease, its possible causes an prevention, and the potential link between chronic inflammation and the development and progression of Alzheimer's disease.

This issue is also a must-read for anyone who feels alone in your efforts to cope with caregiving for a loved one with Alzheimer's.

In no other Memory Bulletin issue will you find such a thorough study of what you need to know about inflammation's impact on your overall health, particularly your cognitive function. Or how overall good nutrition and heart health can contribute to preserving your brain against age-related memory loss.

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SAVE 50%

The wealth of information in Inflammation and Alzheimer's Disease is available to you right now as an instant PDF digital download you can start using right away to make the best decisions about your health. PLUS, you'll get all this invaluable research at 50% off the list price.

Normally, a subscription to the quarterly Johns Hopkins Memory Bulletin is priced at $199 per year for 4 issues, sent out to you in the post via Priority Mail. That's $49.95 per issue.

But for a limited time only, you can get this digital PDF download edition of Inflammation and Alzheimer's Disease from The Johns Hopkins Memory Bulletin for $49.95 only $24.95.

This is news you can use right now to stay as informed and proactive as possible about your mental health and acuity. You will discover emerging news on Alzheimer's Disease, its prevention, treatment, medications, and hopes for a cure.

You will also learn about the potential connection between inflammation and Alzheimer's Disease, and share vital caregiving information in the personal essay "One Lie At A Time: Placing My Father in an Alzheimer's Care Facility," and in the Grand Rounds section of the Memory Bulletin, real questions from our subscribers, with detailed answers from the medical editor Dr. Rabins.

All of the Johns Hopkins memory publications are designed with YOU in mind, the busy person looking for the clearest, most accurate and reliable answers to your many questions about Alzheimer's Disease, from the world's leading experts.

Inflammation and Alzheimer's Disease provides 48 pages of detailed information direct from the doctors and researchers on the front line in the battle against Alzheimer's Disease.

Once you download Inflammation and Alzheimer's Disease, you can start reading it immediately. You'll be able to discuss what you learn with your doctor and loved ones, and apply all you learn immediately, to help you make the most informed decisions about your health to try to prevent Alzheimer's Disease, or make the right treatment decisions for a loved one suffering from Alzheimer's Disease.

As always, your purchase is completely RISK-FREE. Inflammation and Alzheimer's Disease comes with a full 100% money-back guarantee. If you're not satsified with the Inflammation and Alzheimer's Disease issue, simply contact us within 30 days for a full refund.

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