
Gout is a form of arthritis characterized by high levels of uric acid (one of the body's waste products) in the blood and crystals in the joints. These crystals irritate the joints and surrounding tissue. The crystals trigger an inflammatory response and the affected joint becomes red, warm, swollen, and extremely painful. Most commonly, the first attack is in the joint of the big toe. Other vulnerable sites include the knee, wrist, heel, instep, and Achilles tendon.
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All the articles in the Arthritis area are derived from our monthly newsletter, Johns Hopkins Health After 50 and our annual Johns Hopkins White Paper: Arthritis.