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Caffeine: An Unconventional Treatment for Dry Eye

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Caffeine may have benefits that go beyond that early-morning jolt. Researchers in Japan have shown for the first time that caffeine can significantly increase the ability of the eye to produce tears, a finding that could have implications for millions of people with dry eye syndrome.

The study, which was published in Ophthalmology (Volume 119, page 972), examined 41 men and 37 women who were free of high blood pressure, dry eye syndrome and other eye conditions that could affect tear production. The volunteers were divided into two groups for two study sessions: One group received capsules containing caffeine in the first session and a placebo in the second, while the order was reversed for the second group. The amount of caffeine given, in 200 or 300 mg capsules, was based on body weight. (A cup of coffee contains about 150 mg of caffeine.)

The study found that all 78 participants experienced significantly increased tear volume after taking caffeine when compared with the placebo group. What’s more, the researchers reported that tear production was higher among individuals whose DNA samples showed two genetic variations that play important roles in caffeine metabolism.

The suggestion that caffeine could be a therapeutic drug for dry eye syndrome could eventually lead to improved treatments for this common ocular condition that may contribute to eye infections and vision problems.

Posted in Vision on December 6, 2013


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Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or Remedy Health Media, LLC, which has no responsibility for any comments posted on this site.


Caffein eyedrops for high BP patients?

Posted by: DaveHarris | December 7, 2013 3:15 PM

check once the following information. High oxidation-resistance in air at ambient temperature is normally achieved with additions of a minimum of 13% (by weight) chromium, and up to 26% is used for harsh environments.[12] The chromium forms a passivation layer of chromium(III) oxide (Cr2O3) when exposed to oxygen. The layer is too thin to be

Posted by: | December 9, 2013 1:52 AM

HEllo your message above is cut off after "too thin to be.."

Can someone direct me to comments or information about Kidney Cancer sibling-related concerns? Thank you.

Posted by: | December 9, 2013 1:07 PM

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