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Johns Hopkins Health Alert

Can Diet Reduce Your Risk of Prostate Cancer?

Johns Hopkins Health Alerts | Prostate Disorders | Dietary Fat and Prostate Cancer

  • A high intake of vegetables may lower the risk of prostate cancer.

The majority of studies on the relationship between dietary fat and prostate cancer have found that a higher fat intake is associated with an increased risk of prostate cancer. Fat makes up 30% to 40% of the calories in the American diet, compared with 15% in Japan. These differences in fat intake may help explain the much lower death rate from prostate cancer in Japan, as well as the great variability in mortality rates around the world. Another possibility is that people who eat a high-fat diet are less likely to eat healthful foods such as vegetables.

A high intake of vegetables may lower the risk of prostate cancer. According to a study published in the Journal of the National Cancer Institute, men who ate 28 or more servings of vegetables a week had a 35% lower risk of prostate cancer than those who ate 14 or fewer servings per week.

Cruciferous vegetables, such as cabbage and broccoli, appeared to provide a further protective effect against prostate cancer: Men who ate three or more servings of cruciferous vegetables a week (in addition to other vegetables) had a 41% lower risk of prostate cancer than those who ate less than one serving a week. Cruciferous vegetables are rich in substances that induce enzymes to detoxify environmental carcinogens, including the free radicals found in the human diet.

Moderate evidence suggests that other dietary components also may help prevent prostate cancer. High intakes of lycopene (an antioxidant found in tomatoes and tomato-based products) are associated with a 16% to 21% reduced risk of prostate cancer. Taking supplements of selenium (a trace element) reduced the risk of prostate cancer by 66% in one study, and another study found that the incidence of prostate cancer was reduced by 34% in men taking vitamin E supplements.

Johns Hopkins Health Alerts | Prostate Disorders | Dietary Fat and Prostate Cancer

Posted in Prostate Disorders on June 14, 2006
Reviewed July 2009

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Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or MediZine LLC, which has no responsibility for any comments posted on this site.


Men need to consistently add more nutrient dense vegetables, fruits (like pomegranate). it takes years for cancers to develop, which comes from the accumulation of oxidative stress (not enough anti-oxidants), DNA damage and an overwhelmed immune system.

God Bless, Frank Walton www.add17.com

Posted by: frank.walton | July 5, 2006

The information contained above was most helpful. Thank you.

Posted by: shel safer | September 7, 2006

This note on diet is very helpful. Is there a chance of getting the omplete reference from the Journal of the National Cancer Institute? Better still can I get a copy of the article? Thank you. Maxx

Posted by: Maxx | May 19, 2007



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