WELCOME TO JOHNS HOPKINS HEALTH ALERTS!

This free public service from Johns Hopkins Medicine helps keep you up to date on the latest breakthroughs for the most common medical conditions which prevent healthy aging. Browse all the articles via the Health Alert Topics navigation bar on the right, or read the headlines below.


Get the latest news sent straight to your Inbox. Register now for your FREE Johns Hopkins Health Alerts. Check the boxes below for all the topics you are interested in, enter your email address, and click "Send." It's fast, easy, and FREE.   Benefits of Being A Registered User

Enter your email here: (Example: yourname@domain.com)
Please send my alerts as:

We value your privacy and will never rent your email address.Already a Member? Manage your Health Alerts


Johns Hopkins Health Alert

Can Vitamin D Prevent Prostate Cancer?

Comments (2)

If you thought vitamin D's main role was preventing rickets and strengthening bone, think again. Many researchers now believe that the "sunshine vitamin" may one day play a key role in preventing the growth of prostate cancer, and in killing rogue prostate cancer cells that have escaped into the body. The data are quite suggestive and vitamin D is a most promising area for prostate cancer research.

During the past decade, there's been a surge in research into the association between vitamin D and prostate cancer. Multiple studies have reported a link between sub-optimal levels of vitamin D and an increased risk of developing various cancers including prostate cancer, although not all studies have been confirmatory. While these findings are encouraging and could eventually lead to widespread screening for and treatment of vitamin D deficiencies, we still need a large, randomized, placebo-controlled trial to demonstrate whether vitamin D supplementation can actually prevent prostate cancer.

Vitamin D was first isolated by Adolf Windaus, who was awarded the Nobel Prize in 1928 for his work. Vitamin D is not actually a vitamin; it's a hormone. A vitamin is a substance you have to get from food. Vitamin D, however, is manufactured in the body -- the definition of a hormone. While researchers are still working to determine the effects of vitamin D on the prostate, here are some of the heart benefits of this vitamin:

  • Blood pressure regulation. While there is no direct evidence that vitamin D supplementation will lower blood pressure, people with high blood pressure generally have low blood levels of vitamin D.

     

  • Heart attack, stroke, heart failure reduction. A recent study in Circulation reported that events such as heart attacks, strokes, and heart failure were anywhere from 53% to 80% higher in people with low levels of vitamin D in their blood. That risk increased even more in people with high blood pressure.

     

    Low blood levels of vitamin D may increase the risk of heart disease and stroke, especially for people with high blood pressure, according to researchers with the Framingham Heart Study. The scientists followed 1,739 men and women for more than five years and reported that participants with low blood levels of vitamin D were 62% more likely to develop cardiovascular disease than those with higher levels. For those with low vitamin D levels and high blood pressure, cardiovascular risk doubled.

     

  • Helps reduce inflammation. Researchers speculate that more vitamin D could lead to less inflammation in the arteries. Until recently, most researchers believed that heart disease was essentially a "plumbing" problem caused by an accumulation of hardened fat and cholesterol in the coronary arteries, known as plaque. However, an increasing body of evidence now shows that this accumulation of plaque is actually the result of chronic, low-grade inflammation in the coronary arteries. Researchers also believe that in the battle against heart disease, damping down this inflammation is nearly as important as lowering cholesterol.

     

Posted in Prostate Disorders on March 19, 2009
Reviewed September 2011


Medical Disclaimer: This information is not intended to substitute for the advice of a physician. Click here for additional information: Johns Hopkins Health Alerts Disclaimer


Notify Me

Would you like us to inform you when we post new Prostate Disorders Health Alerts?

Post a Comment

Comments

Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or Remedy Health Media, LLC, which has no responsibility for any comments posted on this site.


I feel that Vit D was a significant factor in my experience with P.C. I was diagnosed with prostate cancer in Sept of 07, one of 12 biopsies with a Gleason of 3+3 and a PSA of 4.1. The recommendation by the Dr. was to decide between one of the three conventional approaches within 30 to 60 days; no need to hurry though. I chose to pursue a holistic--homeopathic approach and conducted significant research on my own. A program was developed over time with two holistic-integrative medicine doctors, Dr.’s Jeff Migdow and Liz O’Dair, which included, Bromelain, Vit's C, D, B12, Curcumin (Turmeric), Magnesium, Zinc, Omega 3, Modified Citrus Pectin, and a few other items like these. I also modified diet my by eliminating red meat, high glycemic foods, fats, and dairy products. Feb 08 had a PSA of 2.5. This treatment continued through July 08. There was another PSA June 08 of 2.75. In July of 08 another biopsy was performed in which no cancer was detected. Oct 08 PSA of 2.7 and a Feb 09 PSA of 2.5. I have continued a less strict version of the above regimen since than. I did and still do consume a significant amount of Vit D daily and monitor its level with regular blood tests. This story is a testimonial, not scientific data.

Posted by: Theater Dan | March 31, 2009 9:33 AM

I am new to this with only three PSA data points within the 4 to 10 ng/ml. I am aggressively pursuing this in a natural and nutritional anti-cancer way. From the second to the third data points it dropped by 1.29 in two months.

Check out Life Extension. www.lef.org on Vit. D and much more. I live in the north, and in late 50's and am taking 2000 - 2500 IU Vit. D per day. I am also taking other supplements and anti-cancer diet.

I also highly recommend taking a herbal supplement, Zyflamend, which combines phytochemicals with herbal extracts. (And no known serious side effects) Research was done at Columbia University's Center of Holistic Urology. See www.holisticurology.columbia.edu. My opinion is if the drug companies had results like this you would see it all over the place.

The other choices are cut, burn, or poison; with risks of inpotency, incontinence, and whatever else.

I"m hoping it doesn't come down to that.

Posted by: Andy nonamous | December 4, 2010 12:01 PM

Post a Comment


Already a subscriber?

Login

Forgot your password?

New to Johns Hopkins Health Alerts?

Register to submit your comments.

(example: yourname@domain.com)

(800) 829-0422

Registered Users Log-in:

Forgot Password?

Become a Registered User!
It's fast and FREE!
The Benefits of Being a Registered User

Health Topic Pages

  • Health Alert
  • Special Report

What is this?

XML


Johns Hopkins' Bestsellers Prostate Disorders

Our Featured Titles:

Johns Hopkins Prostate Disorders White Paper

The Johns Hopkins Prostate Bulletin Cover

  • The Johns Hopkins Prostate Disorders Bulletin
    The Johns Hopkins Prostate Disorders Bulletin is a quarterly publication that presents the latest treatment information available on prostate cancer, enlarged prostate (BPH), and prostatitis to help you take charge of your medical care for prostate disease. Each issue is like having an in-depth consultation with a leading specialist. PLUS, subscribe now and get a special discount PLUS 5 FREE Special Reports as INSTANT PDF DOWNLOADS:
    • Special Report #1: BPH (Benign Prostatic Hyperplasia)
    • Special Report #2: Diet and Prostate Health
    • Special Report #3: Treating Overactive Bladder
    • Special Report #4: Chronic Prostatitis: New Research, Renewed Hope
    • Special Report #5: The Radical Prostatectomy

    Click here to read more or order The Johns Hopkins Prostate Disorders Bulletin.


    Related Titles:

    THE JOHNS HOPKINS PROSTATE LIBRARY


    A series of cutting-edge publications designed to address your specific prostate questions.

    • Choosing the Right Treatment for Prostae Cancer
      A must-read primer for any man recently diagnosed with prostate cancer who is looking for answers to pressing questions about treatment options. Our specialists explain in-depth: proactive surveillance, also known as expectant management ... nerve-sparing radical prostatectomy . . . radiation therapy, including EBRT, 3DCRT, IMRT, IGT, and brachytherapy. Written by Jacek L. Mostwin M.D. and colleagues at the world-renowned James Buchanan Brady Urological Institute at Johns Hopkins - the hospital and urology center ranked #1 year after year by U.S. News & World Report -- Choosing the Right Treatment for Prostate Cancer takes you step-by-step through the decision-making process to help you make informed choices.
      Read More

    Restoring Sexual Intimacy After Prostate Cancer Treatment

    The Best Treatment Strategies for BPH

    • The Best Treatment Strategies for BPH
      Written by a team of top specialists at Johns Hopkins' renowned Brady Urological Institute, this essential guide presents the latest thinking on managing benign prostatic hyperplasia (BPH) or enlarged prostate. The report answers dozens of questions from patients searching for practical, no-nonsense advice on living with BPH. It provides a thorough discussion of your surgical options when medication no longer works, weighing the pros and cons of TUNA, TUMT, and TURP. Armed with the information in this guide, you'll be able to meet with your own physician and make the right decisions in your quest for the best possible outcome.
      Read more...

    The Latest Treatments for Advanced Prostate Cancer

    • The Latest Treatments for Advanced Prostate Cancer
      If you've just received the bad news that your prostate cancer has returned, America's #1 Urology Center's specialists offer this up-to-the-minute treatment guide is designed as a detailed primer on advanced prostate cancer, so you can know all your options for dealing with this major health
      Read more...