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Johns Hopkins Health Alert

Is It Safe to Split My Pills?

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Prescription medication is expensive, so many patients split their pills to save money. Is this a good idea? Here’s advice from Johns Hopkins.

Pill splitting is a good way to save on the cost of prescription medication, since a 200-mg dose typically costs the same as a 100-mg dose of a particular drug.

But it is essential to ask your doctor and pharmacist whether your medication can be split safely, because it is very easy to split pills unevenly. For people with certain medical conditions, like epilepsy and some heart problems, an inadequate dose can be dangerous. Correct dosage is also essential for hormone medications. Other medication that shouldn't be split:

  • Extended-release pills that deliver medication over time
  • Combination tablets that contain more than one medication
  • Pills coated to protect the stomach from irritation
  • Pills that crumble easily or are awkwardly shaped
  • Pills that are difficult to swallow because of bitter taste
  • Powder or gel capsules

That said, other medications can be split, like sildenafil (Viagra), certain blood pressure medications, many antidepressants, and most statins. Pills that are scored to make cutting easier indicate approval from the U.S. Food and Drug Administration to split the tablets.

Posted in Prescription Drugs on January 19, 2010


Medical Disclaimer: This information is not intended to substitute for the advice of a physician. Click here for additional information: Johns Hopkins Health Alerts Disclaimer


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Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or Remedy Health Media, LLC, which has no responsibility for any comments posted on this site.


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