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Johns Hopkins Health Alert

Memory Lapses -- Normal Aging or Something More Serious?

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Johns Hopkins doctors explain how cultural attitudes and failure to pay attention may contribute to age-related memory loss.

The brain contains approximately 100 billion neurons (nerve cells). A common misconception is that tens of thousands of neurons die each day. In reality, few neurons die over a person’s lifetime, but they do shrink. This shrinkage may partially explain why mental functioning slows in middle and older age. Serious memory loss does occur when whole clusters of neurons are destroyed by major disorders such as a stroke or Alzheimer's disease.

In addition to the shrinkage of neurons, starting in middle age the brain begins producing smaller quantities of many neurotransmitters—chemical messengers that relay information between nerve cells. Brain blood flow is also reduced 15 to 20 percent between age 30 and age 70, although neuronal shrinkage may account for this because less tissue requires less blood.

Cultural attitudes and preconceptions about aging and memory loss can also influence the occurrence of memory lapses as people age. In one study, researchers compared the memory skills of two groups known to have few stereotypes concerning old age and memory loss (natives of China and deaf Americans) to those of a third group known to have numerous preconceptions about aging and memory loss (hearing Americans). Among these preconceptions is the notion that aging causes an inevitable decline in memory skills. The study results suggest a strong link between culture and memory: The first two groups were less forgetful than the third group, and older Chinese participants performed as well as the younger people in each of these groups. The implication is that if people expect their memory to get worse, they may be less diligent in trying to remember.

Other research indicates that the mental processes required to remember newly acquired information are the same as those needed to retrieve memories from long ago—something most older people do quite well. This implies that older individuals retain the capacity to recall recent events, but the new information is not being recognized as important or is being discarded when transferred to short-term memory. Some researchers interpret this to mean that occasional memory lapses may result from a failure to pay close attention to the information rather than an inability to remember. Thus, it appears that forging new memories depends in large part on staying interested, active, attentive and alert.

Posted in Memory on October 6, 2006
Reviewed June 2011


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Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or Remedy Health Media, LLC, which has no responsibility for any comments posted on this site.


HI, IT ,IS LIKE IN MY HOUSE, MY HUSBAND IS NOT INTERESTET , IN ANY THING,HE IS A PAINTER, FOR OTHER PEOPLE HE DOESE, FOR MY AND I'M GERMAN, LIKE IT CLEAN, THE HOUSE, GARDEN, MY 2 TOY POODLES, CLEAN AND TAKEN CARE OF, SO WHY IS MY HUSBAND, WHO IS AMERICAN ( SOUTHERN) NOT LIKE ME? HE, SOME TIME, SAYS HE DOES NOT UNDER STAND ME, AFTER 24 YRS. I,KNOW,I FORGET A LOT, BUT I CAN REMEMBER ALL THE BAD THINGS, HAPPENT TO ME,WHY? AS, I HAVE FIBROMALGIA, MY UPER AND LOWER SPIN,HURTS ME ALL THE TIME, WITH THIS OSTEOARTHRITIS, SPINAL STENOSIS. THANK YOU AGAIN

Posted by: oldgermanlady2 | April 1, 2007 7:41 PM

This article is very helpful. I am in college doing my assigment paper. I would like to get the refenrences of this article.Thank you.

Posted by: jaybee0207 | February 5, 2010 4:24 AM

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