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Johns Hopkins Health Alert

Questions About Hypertension Medication

Do you take medication to control your high blood pressure? In this Health Alert, Johns Hopkins cardiologist Roger S. Blumenthal answers questions of concern to many of us.

Q. I am not averse to taking medication, but my doctor told me that once I start with a hypertension medication, I would have to take it forever. I am only 51 years old, so "forever" seems like a real long time. What if I were able to stop smoking, and to lose the 40 to 50 pounds the doctor recommends? Would I still need the high blood pressure drugs? Oxford, MI

Dr. Blumenthal answers: Weight loss is highly beneficial in terms of dropping blood pressure for most people. Exercise can also be very helpful in reducing blood pressure in individuals with mild to moderate levels of hypertension. Moderate intensity aerobic exercise has been shown to drop systolic (top number) pressure by 10 to 11 mmHg, and diastolic (bottom number) pressure by 7–8 mmHg.

But the answer to your question about medication depends on the degree of your high blood pressure. It is certainly possible that if your blood pressure is only mildly elevated, a combination of weight loss, exercise, and smoking cessation could lower your blood pressure to the point where medication is not needed. In general, though, most people with high blood pressure tend to remain on their antihypertensive medication for life and often require additional medication to control blood pressure as they age.

Q. My doctor recently started me on hypertension medication. He said my blood pressure was slightly elevated and had not gone down since my exam last year. If my blood pressure is really not that high, is there a risk that the drug will lower my blood pressure too much? Hanover, NH

Dr. Blumenthal answers: It is possible that an antihypertensive medication can work "too well," and cause someone to become hypotensive, that is, for their blood pressure to drop too low.

Physicians typically try to prevent this adverse effect by starting with a low dose of medication and slowly increasing the dosage until optimal blood pressure is achieved. Occasionally, a patient may be more sensitive than expected to a hypertension drug, and sometimes interactions with other medications may enhance the drug's action.

Given that your blood pressure is only "slightly elevated," it is likely that your doctor has prescribed a low dose of medication. If you monitor your blood pressure regularly after starting on the drug, you should be able to avoid hypotension.

Posted in Hypertension and Stroke on December 2, 2008
Reviewed July 2009

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Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or MediZine LLC, which has no responsibility for any comments posted on this site.


How does the adrenal glands effect blood pressure?

Posted by: Paul Schwarze | December 22, 2008

i have a moderate level of hypertension and am having difficulty finding a medication I can tolerate. The first one, attenol taken for a number of years, caused a high ANA reading. The second one, hydrochlorthiazide, also taken for a few years caused/made gout/pseudogout worse, and the third one, diovan, taken for three/four weeks caused unbearable muscle and joint pain and worsened varicose veins. Do you have any suggestion for a medication I might be able to tolerate? I am presently trying to lower my pressure without medication. It is especially high in the morning while lying in bed and goes lower during the day.

Posted by: Judyz | March 17, 2009

I am 65 years old and was on Toprol and Maxide, a diuretic and potassium sparing drug. I was doing well, but my doc changed Toprol to a generic brand of beta blocker and stopped the maxide. He never explained and I am concerned. What about my potassium? Thanks.

Posted by: loosly | May 16, 2009



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