Increase text size: A A A

Type in the condition you need,
or visit Advanced Search

Print this page

Email this to a friend

Comment on this page

Save to my Health Library

Johns Hopkins Health Alert

Can You Prevent BPH With NSAIDs?

If you take a daily aspirin for your heart, you may be doing your prostate a favor as well. Emerging research suggests that daily use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, or naproxen, reduces the risk of developing benign prostatic hyperplasia (BPH). But the benefits of NSAIDs to the prostate may not be worth the risk. Read what Johns Hopkins recommends …

In a long-term study of NSAIDs and BPH, researchers monitored the prostate health of nearly 2,500 men, ages 40–79, for more than 10 years. At the onset of the study, all of the men answered a questionnaire about their BPH symptoms, and about 20% also underwent clinical evaluations for BPH, including a digital rectal exam, an ultrasound of their prostate, and blood tests to determine their prostate-specific antigen (PSA) level.

The same process was repeated every two years to detect and track BPH symptoms. None of the men had BPH symptoms at the study's outset, and about one third reported taking an NSAID every day. Among the daily NSAID users, 80% took aspirin; the rest took other common anti-inflammatory medications, such as ibuprofen (Motrin and others) or naproxen (Aleve and others).

Compared with men who did not take the medications, daily NSAID users were 27% less likely to report that their urinary symptoms (such as difficulty urinating or the need to urinate more urgently or more often) were moderate to severe, 47% less likely to have prostate enlargement, 48% less likely to have an elevated PSA level, and 49% less likely to report a weak urinary stream.

These findings suggest that taking a daily NSAID reduces the risk of developing BPH symptoms, and results from several previous studies seem to indicate that regular use of aspirin or other NSAIDs may also lower the possibility of developing prostate cancer.

What Should You Do Now? At this point, doctors do not recommend taking a daily NSAID strictly to improve prostate health. More research is needed to confirm the apparent beneficial effects of NSAIDs on the prostate. Plus, long-term use of these medications can lead to dangerous side effects, such as gastrointestinal bleeding and kidney problems, in some people. And a growing body of evidence suggests that, with the exception of aspirin, NSAIDs can increase your chances of having a heart attack or stroke if you have or are at risk for heart disease.

For now, if your doctor has prescribed a daily aspirin to help prevent heart disease—or you are taking prescribed NSAIDs for arthritis—you may be reaping prostate benefits as well. And, while there's no specific BPH prevention diet, it won't hurt to eat more veggies and pass up that extra slice of bread. If you lose weight in the process, all of your organs will thank you.

Posted in Enlarged Prostate on March 31, 2009
Reviewed July 2009

Comments

Post a Comment

Health Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the Johns Hopkins editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Johns Hopkins Medicine or MediZine LLC, which has no responsibility for any comments posted on this site.




Post a Comment


New to the Johns Hopkins Health Alerts?
Signup

User Name:


This appears next to your comment.


Email Address:

(this will not be posted)
This will be your login ID.

Password:

Confirm Password:


Receive Health Alerts?

Notify me when new comments are posted?

Comment (offensive materials and/or spam will be removed, no HTML allowed)

Already a subscriber?
Login

Email:

Password:


Forgot your password?

(800) 829-0422

Registered Users Log-in:

Email:

Password:

Remember me
Forgot Password?

Become a Registered User!
It's fast and FREE!
The Benefits of Being A Registered User

Health Topic Pages

Arthritis +Add
Back Pain & Osteoporosis +Add
Cancer
Caregivers | Caregiving
Colon Cancer +Add
Complementary Medicine
Depression & Anxiety +Add
Diabetes +Add
Digestive Health +Add
Enlarged Prostate +Add
Exercise and Fitness
Healthy Living +Add
Heart Health +Add
Hypertension & Stroke +Add
Lung Disorders +Add
Memory +Add
Men's Health
Nutrition +Add
Prescription Drugs +Add
Prostate Disorders +Add
Sexual Health
Vision +Add
Weight Control +Add
Women's Health
Health Alert Special Report


© 2009 MediZine LLC. All rights reserved.
Contact Us
customerservice@johnshopkinshealthalerts.com