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Johns Hopkins Health Alert

Don't Rely On Virtual Colonoscopy For Colon Cancer Screening

Johns Hopkins Health Alerts | Digestive Health | Virtual Colonoscopy for Colon Cancer Screening

  • Biopsy samples cannot be taken with a virtual colonoscopy, and polyps cannot be removed as they can during a standard colonoscopy.

A colonoscopy is considered the gold standard as a screening test for colon cancer. The test requires the insertion of a long flexible viewing tube—a colonoscope—through the entire colon and, at times, the lower portion of the small intestine. By means of the colonoscope, a gastroenterologist can view the inside of the colon and also take biopsy samples and remove any abnormal growths that may develop into colon cancer.

Although patients undergoing colonoscopy are sedated, colonoscopy can cause abdominal cramping, bloating, and a need to pass gas. Patients must also wait until the sedation wears off, which can take an hour, and someone must drive them home. Serious complications of colonoscopy are rare, but can include perforation of the colon.

It is understandable that a “virtual” colonoscopy—a relatively new technology—sounds more appealing. Patients are not sedated, and the procedure is much less invasive. A tube is inserted into the patient’s rectum and the colon is filled with air so that its entire length can be viewed using computed tomography (sometimes called a CT or CAT scan).

However, patient preparation is the same as it is for a conventional colonscopy: A mainly liquid diet must be followed for up to three days before the colonoscopy and a strong laxative must be taken the evening prior to the test to ensure the colon is cleansed for viewing. And although virtual colonoscopy is quicker, safer, and cheaper than traditional colonoscopy—and nearly as accurate in detecting “clinically relevant” polyps—a number of drawbacks make virtual colonoscopy an undesirable option for most people.

For example, biopsy samples cannot be taken with a virtual colonoscopy. If any abnormalities are detected, patients still require a standard colonoscopy for confirmation of the diagnosis. In addition, polyps cannot be removed as they can during a standard colonoscopy. Also, in a survey of screenings at nine major hospitals, virtual colonoscopy proved significantly less capable than standard colonoscopy of detecting small polyps (6 mm or less).

In the future this test will be most useful for people at low risk for colon cancer. Currently, a virtual colonoscopy is not recommended for routine colon cancer screening purposes. You are an appropriate candidate for virtual colonoscopy only if you have a medical condition that makes a standard colonoscopy risky or physically difficult.

Johns Hopkins Health Alerts | Digestive Health | Virtual Colonoscopy for Colon Cancer Screening

Posted in Digestive Health on June 28, 2006
Reviewed June 2008

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Users and editors may post comments here at their own discretion. The views expressed do not constitute medical advice and do not represent the position of Johns Hopkins Medicine or University Health Publishing, which has no responsibility for its content.


Thanks to a virtual colonoscopy performed 6 years ago which spotted an aneurism in my right illiac artery, and annual echographies thereafter, an operation which probably saved my life was performed last March to install an endoprothesis in my left and right illiac arteries and the base of my aorta.

I will gladly supply any additional information in this regard.

Jacques Bisaillon Laval, Canada

Posted by: bisaijr | July 6, 2006

I'd love to know what the odds are in Tampa FL of having your colon perforated during an optical colonoscopy procedure? It happens all the time here, and for some ridiculous reason, most insurance companies won't cover a virtual colonoscopy which is more accurate, no sedation needed and non invasive to the patient. I'd guess about 1 in ten people.....am I correct?

Posted by: serialmom12 | September 18, 2007

The cost of the virtual colonoscopy performed on me in the year 2000 was not covered by the provincial insurance health plan but 80% of that cost was reimbursed to me by my private insurance plan.

Jacques Bisaillon Laval, Canada

Posted by: bisaijr | September 18, 2007



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