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Johns Hopkins Health Alert

Once-a-Year Reclast for Osteoporosis

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UPDATE

 

As part of our ongoing effort to ensure that this website is up to date, we have determined that the information in the article Once-a-Year Reclast for Osteoporosis is no longer current, and has therefore been removed.   

 

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Posted in Back Pain on June 27, 2008
Reviewed June 2011


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April 30, 2008 — Women who have ever taken alendronate (Fosamax, Merck), the bisphosphonate widely prescribed for preservation of bone density that recently went off patent, have an increased risk of developing atrial fibrillation (AF), according to a population-based, case-control study in the April 28, 2008 Archives of Internal Medicine.

Based on this latest information do the benefits in fracture prevention from taking alendronate sill outweigh the possible risk of atrial fibrillation?

Posted by: MrBones | June 28, 2008 10:11 AM

All medications are a balancing act. Everything can have a side effect, including over the counter medications. Even aspirin can be lethal to some people.

Having said that, the trouble with Atrial fibrillation is that there are not really any effective treatments for it at this time, as compared with different alternatives at the moment for osteo.

Therefore, the best thing to do is talk with your doctor about risk versus benefit ratio.

Posted by: Jo | July 3, 2008 3:18 PM

I took Fosamax ONE day. ONE pill. Exactly as directed. About 7:00 p.m. my wrist started to hurt. Then it was my fingers, my hip, my ankles, my jaw. I took some aspirin. Woke up at 1:00 a.m. in terrible pain. I could hardly hobble to the kitchen for more aspirin/ibuprofen. I had to wake my husband to get the cap off the bottle. I thought my right femur was going to break each time I sat down or stood up. Every bone in my body was a source of pain - even my toes. Long story short, I spent two days in Hell before it even began to let up. That was back in March of 2010. It is now nearing mid-July and I still have lingering pain in my right femur and one of my fingers is bent.

I am not the only one this has happened to. I got off easy compared to some. The scariest thing is that nobody is taking this seriously. Women report that their doctors don't believe them. Thank God I only used a pill and didn't get one of those 1/yr IVs!

Another thing I want to mention is that, on a much smaller scale, Glucosamine Condroiton has the same effect on me. I am curious to know if other women who've had problems with bisphosphonates also have problems with Glucosamine Condroiton.

Posted by: kelltic | July 10, 2010 9:56 AM

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